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Gisela Soledad Gualdoni

Current position

Postdoctoral training ANPyCT

Faculty of Exact and Natural Sciences, University of Buenos Aires

Bs. As., Arg.

Sept 2021 - Sept 2019

  • Biology of Reproduction in mammals: male reproductive physiopathology, gonadal dysfunction and infertility – Gestational-placental physiology.
  • Advisor: Dr. Elisa Cebral

Assistant teacher of Histology

Faculty of Medicine, University of Buenos Aires.

Bs. As., Arg.

Present - March 2016

Education

Ph.D. in Biological Sciences

Faculty of Exact and Natural Sciences, University of Buenos Aires

Bs. As., Arg.

July 2019 - June 2014

  • Dissertation: Does angiogenesis contribute to the perpetuation of a chronic inflammatory state of the testicle that results in infertility?
  • INBIOMED (CONICET/UBA), Faculty of Medicine, University of Buenos Aires
  • Advisor: Dr. Vanesa Guazzone

Licenciate in Biological Sciences

Faculty of Exact and Natural Sciences, University of Buenos Aires

Bs. As., Arg.

May 2014 - March 2007

  • Dissertation: Indolamine 2,3-dioxygenase (IDO): Participation in the testicular immune-privilege.
  • INBIOMED (CONICET/UBA), Faculty of Medicine, University of Buenos Aires
  • Advisor: Dr. Vanesa Guazzone

Secondary School graduate

Nuestra Señora de Belén

Bs. As., Arg.

Dec 2006 - March 2003

  • Bachiller

Postgraduate courses

The placenta: origin of chronic diseases in adults (60hs)

Faculty of Pharmacy and Biochemistry, University of Buenos Aires

Bs. As., Arg.

Nov 2021 - Nov 2020

Embryo-Placental Development Biology. Abnormal events and teratogenicity (109hs)

Faculty of Exact and Natural Sciences, University of Buenos Aires

Bs. As., Arg.

March 2021 - March 2020

Statistics applied to health sciences (88hs)

Faculty of Pharmacy and Biochemistry, University of Buenos Aires

Bs. As., Arg.

July 2019 - July 2018

Optical and Fluorescence Microscopy I (80 hs)

Faculty of Exact and Natural Sciences, University of Buenos Aires

Bs. As., Arg.

June 2019 - June 2018

Theoretical-practical course on Oxygen Toxicity and Free Radicals (72hs)

Faculty of Exact and Natural Sciences, University of Buenos Aires

Bs. As., Arg.

April 2019 - April 2018

Theoretical-practical course in cell biology of the endothelium. Dynamics of the vascular extracellular matrix (48hs)

Faculty of Pharmacy and Biochemistry, University of Buenos Aires

Bs. As., Arg.

April 2018 - April 2017

Experimental design and work of the sample in essays with laboratory animals XII edition (40hs)

Central Bioterium of the Faculty of Exact and Natural Sciences, University of Buenos Aires

Bs. As., Arg.

July 2018 - July 2017

Theoretical-practical course of Animal Tissue Culture - Applications in Biotechnology (135hs)

Institute of Oncology Angel Roffo, University of Buenos Aires

Bs. As., Arg.

Oct 2017 - Oct 2016

Laboratory Animals XVIII edition (80hs)

Central Bioterium of the Faculty of Exact and Natural Sciences, University of Buenos Aires

Bs. As., Arg.

July 2017 - July 2016

Theoretical-practical basis of flow cytometry (40hs)

Auditorium of the Official College of Pharmacists and Biochemists

Bs. As., Arg.

Nov 2016 - Nov 2015

Technical Skills

  • Histology techniques: (paraffin, cryostat)

  • Immunohistochemistry: IP, IF, TUNEL

  • Histopathology

  • Morphometric analysis (Image J, Adobe Photoshop)

  • RT-PCR

  • Western Blot

  • ELISA

  • Enzymatic zymography

  • Oxidative stress techniques

  • Animal handling (mouse, rat)

  • Cell culture (testicular explants)

Research projects and activities

Cellular processes that occur during implantation and placentation in domestic carnivores. Basic aspects and implications (ANPyCT, PICT-2017-3530)

Livestock and Fishing Technology, National University of La Plata

Bs. As., Arg.

March 2021 - Dec 2018

  • Role: Postdoctoral fellow

Is vitamin D3 capable of modulating the immune response in a condition of chronic testicular inflammation? (ADUBA, Scholarship for a Research Project for teachers of the University of Buenos Aires)

INBIOMED, Faculty of Medicine, University of Buenos Aires

Bs. As., Arg.

Dec 2019 - March 2019

  • Role: Principal researcher

Pathogenesis of Autoimmune Orchitis: Is there a relationship between HMGB1 and the angiogenesis process during inflammation? (UBACyT 20020170100307BA)

INBIOMED, Faculty of Medicine, University of Buenos Aires

Bs. As., Arg.

March 2019 - Dec 2018

  • Role: doctoral fellow

Varicocele: Role of the immune response in the etiology of the disease (UBACyT 2014-2017 GEF)

INBIOMED, Faculty of Medicine, University of Buenos Aires

Bs. As., Arg.

March 2017 - Dec 2014

  • Role: doctoral fellow

Mechanisms and factors involved in angiogenesis in the normal testis and in inflammatory conditions (PIP-CONICET 930)

INBIOMED, Faculty of Medicine, University of Buenos Aires

Bs. As., Arg.

March 2014 - May 2012

  • Role: Undergraduate fellow

Study of the pathogenic role of IL-17 in the rat testis with chronic inflammation (UBACyT 20020130200130BA)

INBIOMED, Faculty of Medicine, University of Buenos Aires

Bs. As., Arg.

March 2014 - Dec 2012

  • Role: Undergraduate fellow

Indolamine 2,3-dioxygenase (IDO): Participation in the testicular inmune-privilege (UBACyT 20020100200040)

INBIOMED, Faculty of Medicine, University of Buenos Aires

Bs. As., Arg.

March 2013 - Dec 2011

  • Role: Undergraduate fellow

Publications

Languages

  • Spanish: Native

  • English: Upper Intermediate

Maternal perigestational alcohol consumption up to early mouse gestation induces fetal malformation and abnormal placental development.

N/A

N/A

2020

  • Pérez-Tito L, Gualdoni GS, Sobarzo C, Bevilacqua E, Cebral E (*: equal contribution)
  • In preparation

Comparative involvement of matrix metalloproteinases in trophoblast invasiveness during endotheliochorial and haemochorial placentation

N/A

N/A

2020

  • Gualdoni GS, Diessler M, Gomez Castro G, Hernández R, Barbeito C, Cebral E
  • Trophoblast Research of Placenta, Review by invitation. In press.

Perigestational alcohol consumption induces altered early placentation and organogenic embryo growth restriction by disruption of trophoblast angiogenic factors.

N/A

N/A

2020

  • Gualdoni GS, Ventureira MR, Coll TA, Palomino WA, Barbeito C, Cebral E
  • Reproductive BioMedicine Online, in press.
  • DOI

Relevance of angiogenesis in autoimmune testis inflammation.

N/A

N/A

2020

  • Gualdoni GS, Jacobo PV, Sobarzo CM, Pérez CV, Haro Durand LA, Theas MS, Lustig L, Guazzone VA
  • Molecular Human Reproduction, in press.
  • More info here

Role of indoleamine 2, 3 - dioxygenase (IDO) in testicular immune-privilege.

N/A

N/A

2019

  • Gualdoni GS, Jacobo PV, Sobarzo CM, Pérez CV, Matzkin ME, Höcht C, Frungieri MB, Hill M, Anegon I, Lustig L, Guazzone VA
  • Scientific Reports, 1, 15919.
  • DOI

Dual roles of endogenous and exogenous galectin-1 in the control of testicular immunopathology.

N/A

N/A

2015

  • Pérez CV, Gómez L, Gualdoni GS, Lustig L, Rabinovich G, Guazzone VG
  • Scientific Reports, 5, 12259.
  • DOI

Grants, Awards and Fellowships

Postdoctoral Fellow

IBBEA, Faculty of Exact and Natural Sciences, University of Buenos Aires

Bs. As., Arg.

Sept 2021 - Sept 2019

  • National Agency of Scientific and Technical Promotion (ANPyCT)
  • Advisor: Dr. Elisa Cebral

Travel Fellowship

II International Scientific Meeting, VII Regional Scientific Meeting, VI National Congress of Laboratory Animal Science and Technology

Rosario, Arg.

Nov 2020

  • Argentine Association of Science and Technology of Laboratory Animals (AACYTAL)
  • Attendant
  • Sponsored by LAB DIET/SERVIVET

Travel Fellowship

9th International Meeting of LASBRA: Determinants of Alcoholism: bridging the gap between epidemiological and basic research

Córdoba, Arg.

Nov 2019

  • Latin American Society for Biomedical Research on Alcoholism (LASBRA)
  • Attendant

First Prize in the area “Scientific Production of Knowledge”

2nd Conference: Problematic Consumption of Substances and Alcohol, “Accessibility to care. A perspective of rights”

Bs. As., Arg.

Sep 19, 2019

  • Effects of alcohol consumption on the maternal and paternal germ line and early embryo-placental teratogenic risk.
  • Gualdoni GS, Ventureira MR, Cebral E

Doctoral Fellow

INBIOMED, Faculty of Medicine, University of Buenos Aires

Bs. As., Arg.

April 2019 - June 2014

  • National Council for Scientific and Technical Research (CONICET)
  • Advisor: Dr. Vanesa Guazzone

Travel Assistance Award

37th Annual Meeting of ASRI: Bridging Immunity with Infection, Inflammation and Implantation for Better Reproductive Health

Chicago, USA

Sept 2017

  • American Society for Reproductive Immunology (ASRI)
  • Attendant

Selected Talks and Scientific Presentations

Dysregulation of labyrinthine angiogenesis-vascularization and embryo-feto-placental growth in a preclinical model of maternal alcohol consumption.

IV Joint Meeting of Biological Societies of the Argentine Republic (SAB): New Evidences and Changes in Paradigms in Biological Sciences

Bs. As., Arg.

Sept 2020

  • Gualdoni GS, Ventureira M, Barbeito C, Cebral E. Abstract book SAB, p. 207, 2020.
  • Poster presentation
  • National meetings

Fetal placental-heart disease and angiogenesis in a murine model of maternal alcohol intake.

III Colombian Symposium on Placenta and Maternal-Fetal Interaction

Cali, Col.

Aug 2020

Placental dysmorphology and abnormal angiogenesis at mid- and late gestation following maternal alcohol consumption in mouse.

IXI LASBRA International Meeting, Determinants of Alcoholism: bridging the gap between epidemiologic and basic research

Córdoba, Arg.

Nov 2019

  • Gualdoni GS, Ventureira MR, Barbeito C, Elisa Cebral E. The Journal of Fetal Alcohol Spectrum Risk & Prevention (JFASRP), e57, doi: 10.22374/jfasrp.v2i1.7
  • Poster presentation
  • International meetings

Long-term fetal developmental alterations and cardiopathy associated with oxidative stress induced after perigestational alcohol consumption up to organogenesis, in mouse.

IXI LASBRA International Meeting, Determinants of Alcoholism: bridging the gap between epidemiologic and basic research

Córdoba, Arg.

Nov 2019

  • Ventureira MR, Elía E, Gualdoni GS, Cebral E. The Journal of Fetal Alcohol Spectrum Risk & Prevention (JFASRP), e76, doi: 10.22374/jfasrp.v2i1.7
  • Poster presentation
  • International meetings

Placenta–heart axis: abnormal cardiovascular development and VEGF expression after perigestational alcohol intake at mid-gestation in mouse.

International Federation of Placenta Associations (IFPA) and 8th Latin American Symposium on Maternal-Fetal Interaction and Placenta (VIII SLIMP)

Bs. As., Arg.

Sept 2019

  • Ventureira MR, Sobarzo C, Gualdoni GS, Barbeito C, Cebral E. Placenta, 83,1–118, 2019.
  • Poster presentation
  • International meetings

Melatonin treatment prevents the progression of experimental autoimmune orchitis in rats.

Meeting of the Argentine Society for Clinical Research (SAIC) and the Argentine Society of Physiology (SAFIS)

Bs. As., Arg.

Nov 2018

  • Mendez CS, González LN, Gualdoni GS, Imsen M, Amarilla MS, Sobarzo C, Lustig L, Jacobo PV, Theas MS. Rev. Medicina 78 (III), 244, 2018.
  • Poster presentation
  • National meetings

Does angiogenesis contribute to the perpetuation of a chronic inflammatory state of the testicle that results in infertility?

INBIOMED, Faculty of Medicine, University of Buenos Aires

Bs. As., Arg.

Oct 2018

  • Seminars

Factors involved in the angiogenic process in the testis under chronic inflammation.

Meeting of the Argentine Society for Clinical Research (SAIC) and the Argentine Society of Physiology (SAFIS)

Mar del Plata, Arg.

Nov 2017

  • Jacobo PV, Pérez CV, Gualdoni GS, Sobarzo CM, Lustig L, Guazzone V, Theas MSu. Rev. Medicina 77 (1937), 532, 2017.
  • Poster presentation
  • National meetings

Relevance of angiogenesis in autoimmune testis inflammation.

37th Annual Meeting of ASRI

Chicago, USA

Sept 2017

  • Gualdoni GS, Jacobo P, Sobarzo CM, Theas MS, Lustig L, Guazzone VA. Annual ASRI Book, 78 (1), 38, 2017.
  • Oral presentation
  • International meetings

Relevance of the angiogenesis phenomenon in the development of an experimental autoimmune orchitis associated with infertility.

Meeting of the Argentine Society for Clinical Research (SAIC) and the Argentine Society of Physiology (SAFIS)

Mar del Plata, Arg.

Nov 2015

  • Gualdoni GS, Jacobo P, Sobarzo CM, Lustig L, Theas MS, Guazzone VA. Rev. Medicina 275 (192), 143, 2015.
  • Poster presentation
  • National meetings

Role of indolamine 2,3-dioxygenase (IDO) in testicular immune-privilege.

IMMUNOCOLOMBIA2015, 11th Congress of the Latin American Association of Immunology

Medellin, Col.

Sept 2015

  • Gualdoni GS, Jacobo PV, Sobarzo CM, Hotch C, Hill M., Anegon I, Lustig L, Guazzone VA. Front. Immunol. doi:10.3389/conf.fimmu.2015.05.00105, 2015
  • Poster presentation
  • International meetings

Indolamine 2,3-dioxygenase (IDO): Participation in the testicular immune-privilege.

INBIOMED, Faculty of Medicine, University of Buenos Aires

Bs. As., Arg.

May 2015

  • Seminars

Endogenous Galectin-1 controls testicular pathology through modulation of germ cells apoptosis.

14th International Symposium for Immunology of Reproduction

Boston, USA

June 2013

  • Pérez CV, Gómez L, Gualdoni GS, Rabinovich G, Lustig L, Guazzone VA. American Journal of Reproductive Immunology 69 (2), 59, 2013.
  • Poster presentation
  • International meetings

Preclinical experimental murine models for the detection and evaluation of gametic-embryonic abnormalities after maternal alcohol consumption.

II International Scientific Meeting, VII Regional Scientific Meeting, VI National Congress of AACYTAL

Rosario, Arg.

Nov 1, 2011

  • Gualdoni GS, Ventureira MR, Sobarzo C, Cebral E
  • Poster presentation
  • National meetings

Teaching Experience

Teaching staff in Biological Sciences (Middle and Higher Education in Biology specialty)

Faculty of Exact and Natural Sciences, University of Buenos Aires

Bs. As., Arg.

Present - March 2019

  • Pedagogical training

Assistant teacher

2nd Chatedra of Histology, Embriology, Celular Biology and Genetics, Faculty of Medicine, University of Buenos Aires

Bs. As., Arg.

Present - March 2019

  • -Histology
  • Undergraduate teaching

The design of the teaching proposal in a virtual environment

Faculty of Medicine, University of Buenos Aires

Bs. As., Arg.

June 2020

  • Pedagogical training

Assistant teacher

Department of Biodiversity and Experimental Biology, Faculty of Exact and Natural Sciences, University of Buenos Aires

Bs. As., Arg.

March 2020

  • -Biology of embryo-placental development. Abnormal events and teratogenicity
  • Undergraduate teaching

Training of Martín Pizzini, Medical student, Faculty of Medicine

INBIOMED, University of Buenos Aires

Bs. As., Arg.

July 2019 - July 2018

  • Training and qualification of undergraduate students

Training of Sheila Castañeda, Biotechnology student, UADE

INBIOMED, University of Buenos Aires

Bs. As., Arg.

March 2019 - March 2017

  • Pedagogical training

Assistant teacher

Department of Biodiversity and Experimental Biology, Faculty of Exact and Natural Sciences, University of Buenos Aires

Bs. As., Arg.

March 2017 - Aug 2016

  • -Compared Animal Physiology
  • Undergraduate teaching

Assistant School for Histology

2nd Chatedra of Histology, Embriology, Celular Biology and Genetics, Faculty of Medicine, University of Buenos Aires

Bs. As., Arg.

Dec 2015 - March 2015

  • Posdoctoral Course teaching

Assistant teacher

Department of Biodiversity and Experimental Biology, Faculty of Exact and Natural Sciences, University of Buenos Aires

Bs. As., Arg.

March 2015 - March 2013

  • Introduction to Zoology, Animal Histology, Compared Endocrinology

Networks and dissemination

Member of the national intersectoral network: “Promotion Team for Intersectoral Prevention of Alcohol Consumption” (EPPICA)

N/A

Bs. As., Arg.

Present - Sept 2019

  • Training and qualification of undergraduate students